What scientific publications reference Cospheric's Polystyrene Microspheres?
Here is a sample of articles that reference this product line:
Palaniappan, S., Sadacharan, C.M. & Rostama, B. Polystyrene and
Polyethylene Microplastics Decrease Cell Viability and Dysregulate
Inflammatory and Oxidative Stress Markers of MDCK and L929 Cells In
Vitro. Expo Health 14, 75–85 (2022).
Scientists treated L929 murine fibroblasts and Madin–Darby canine kidney (MDCK)
epithelial cell lines with 1 μg/mL, 10 μg/mL, or 20 μg/mL of
polyethylene (PE) or polystyrene (PS) microspheres in vitro for 6 and 24
h and measured the resulting changes in cell viability, metabolism, and
transcriptional expression of inflammatory cytokines and antioxidant
enzymes. They observed dose-dependent decreases in cell viability
corresponding to increases in doses of both PE and PS.
Zhao, S., Danley, M., Ward, J.E., Lia, D., Mincer, T., An approach for extraction, characterization and quantitation of microplastic in natural marine snow using Raman microscopy. Analytical Methods.
Researchers present a new dual density separation method employing sodium iodide
extraction followed by methanol precipitation, specifically designed for
microplastic isolation and identification in natural marine snow
Senčar. J., Hammerschmidt, N., Martins, D., Jungbauer, A. A narrow residence time incubation reactor for continuous virus inactivation based on packed beds, New Biotechnology, Volume 55, 2020, Pages 98-107, ISSN 1871-6784,
A narrow residence time distribution (RTD) is highly desirable for
continuous processes where a strict incubation time must be ensured,
such as continuous virus inactivation. A packed bed reactor
with non-porous inert beads was developed to achieve narrow RTDs. Results indicated that viruses travelled through the
column at rates independent of size. This proposal of packed beds as
incubation chambers for continuous virus inactivation is simple,
scalable, and can be realized as single-use devices.
Gray, A.D. and Weinstein, J.E. (2017), Size- and shape-dependent effects
of microplastic particles on adult daggerblade grass shrimp (Palaemonetes pugio). Environmental Toxicology and Chemistry, 36: 3074-3080.
The objective of the present study was to characterize the size- and
shape-dependent effects of microplastic particles (spheres, fibers, and
fragments) on the adult daggerblade grass shrimp (Palaemonetes pugio).
Grass shrimp were exposed to 11 sizes of plastic: spheres (30, 35, 59,
75, 83, 116, and 165 μm), fragments (34 and 93 μm), and fibers (34 and
93 μm) at a concentration of 2000 particles/400 mL (= 50 000
particles/L) for 3 h. Following exposure, grass shrimp were monitored
for survival, ingested and ventilated microplastics, and residence time.
Clark, L., DiBenedetto, M., Ouellette, N., Koseff, J. Settling of inertial nonspherical particles in wavy flow. Physical Review Fluids, 5, 124301
In this study scientists experimentally investigate the settling of plastic rods, disks,
and spheres in wavy flows. They find that the average vertical velocities
of the particles can both increase and decrease in waves, relative to
the particle settling velocity in quiescent flow and demonstrate that accounting for the variation of particle settling velocities with shape
and inertia in models is necessary to improve the accuracy of
predictions of the transport of microplastics in the ocean.
Nedelcu, O. T., Tibeica, C., Parvulescu, C., Sandu, T. Experiments on
dielectrophoretic handling and holographic microscopy imaging of
microparticles with targeted applications to biological cell
manipulation and visualisation. 2022 International Semiconductor Conference (CAS), Poiana Brasov, Romania, 2022, pp. 265-268.
The dielectrophoretic separation of microparticles is achieved by
controlling the applied frequencies and voltages which depend on liquid
and suspension dielectric properties. Furthermore, image acquisitions of
separated microparticles were performed by digital lensless holographic
microscopy and 3D digital image reconstruction. The results show that
suspended dielectric microparticles can be manipulated, separated, and
holographically visualized, opening the possibility to use the same
setup for living cells.
Hwang, J., Choi, D., Han, S. et al. Potential toxicity of polystyrene microplastic particles.
Scientific Reports 10, 7391 (2020).
Primary polystyrene (PS) particles were the focus of this study, and scientists investigated the potential impacts of these microplastics on human
health at the cellular level. It was determined that polystyrene particles were
potential immune stimulants that induced cytokine and chemokine
production in a size-dependent and concentration-dependent manner.
Mattioda V, Benedetti V, Tessarolo C, Oberto F, Favole A, Gallo M,
Martelli W, Crescio MI, Berio E, Masoero L, Benedetto A, Pezzolato M,
Bozzetta E, Grattarola C, Casalone C, Corona C, Giorda F.
Pro-Inflammatory and Cytotoxic Effects of Polystyrene Microplastics on
Human and Murine Intestinal Cell Lines. Biomolecules. 2023; 13(1):140.
Microplastics (MPs) are ubiquitous pollutants but, still, little is
known about their effects on human and animal health. Researchers aim
to investigate cytotoxicity, oxidative stress, inflammation and
correlated gene modulation following exposure to polystyrene
microplastics (PS-MPs) in HRT-18 and CMT-93 epithelial cell lines.
Im, J., Eom, HJ. & Choi, J. Effect of Early-Life Exposure of
Polystyrene Microplastics on Behavior and DNA Methylation in Later Life
Stage of Zebrafish.
Arch Environ Contam Toxicol 82, 558–568 (2022).
In this study, researchers investigated the neurodevelopmental toxicity of polystyrene microplastics (PSMPs) in the zebrafish Danio rerio
under different exposure scenarios. Zebrafish were exposed to PSMPs
during embryonic stage and then allowed the fish to recover. The
neurodevelopmental toxic responses were investigated using fish behavior
and behavior-related gene expression.